Prevalence of Phototherapy-Induced Hypocalcemia
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Abstract:
Background: Hyperbilirubinemia is the single most common abnormal physical finding in the first week of life and is commonly managed by phototherapy with its inherent complications. A lesser known complication of the phototherapy is hypocalcemia. Objective: To study the prevalence of phototherapy-induced hypocalcemia and to compare it between premature and full-term babies. Methods: This study was performed on 153 jaundiced neonates (62 premature, 91 full-term) that were managed with phototherapy. These neonates were completely normal on physical examination. Serum calcium was checked on arrival, 48 hours after starting phototherapy and 24 hours after discontinuation of the treatment. The first samples were considered as controls. A comparative study was made between these groups to determine the prevalence of hypocalcemia. Results: Twenty- two neonates (14.4%) developed hypocalcemia. There were significant differences between the prevalence of hypocalcemia in premature (22.6%) and full-term neonates (8.7%) (p= 0.018). None of the hypocalcemic neonates was symptomatic clinically. Serum levels of calcium returned to normal 24 hours after discontinuation of phototherapy in almost all hypocalcemic neonates. Conclusion: The study shows that neonates under phototherapy are at high risk of hypocalcemia. This risk is greater in premature neonates.
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prevalence of phototherapy-induced hypocalcemia
background: hyperbilirubinemia is the single most common abnormal physical finding in the first week of life and is commonly managed by phototherapy with its inherent complications. a lesser known complication of the phototherapy is hypocalcemia. objective: to study the prevalence of phototherapy-induced hypocalcemia and to compare it between premature and full-term babies. methods: this s...
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Hyperbilirubinemia is a common and in most cases benign clinical condition in neonates. Phototherapy is used for management of neonatal hyperbilirubinemia[1]. Phototherapy may lead to complications including skin rash, diarrhea, hyperthermia, chills, dehydration, DNA damage to lymphocytes, retinal degeneration, bronze baby syndrome especially in cholestatic jaundice and PDA opening in LBWs and ...
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Bakground: Phototherapy plays a significant role in the treatment and prevention of hyperbilirubinemia as well as the management of subsequent complications in the newborn. However, this treatment modality may itself result in the development of hypocalcaemia and create serious complications including convulsion and related conditions. Objective: This study was under-taken to investigate photo...
full textPhototherapy Induced Hypocalcemia in Neonates
The objective is to study the effect of phototherapy on serum calcium in neonates. A Cross sectional study was performed in a Tertiary care centre, Gandhi Medical College, Bhopal. Study group includes neonates with hyperbilirubinemia requiring phototherapy and control group include neonates having hyperbilirubinemia in physiological range. Study group and control group includes 60 and 30 neonat...
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Journal title
volume 27 issue 4
pages 166- 168
publication date 2015-11-30
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